Buffalo rookie Mike Gillislee ran 50 yards for a touchdown with 2:25 remaining to secure a 16-6 win for the Bills over the Dallas Cowboys on Sunday.
finished with 93 yards rushing and led a ground attack that combined for 236 yards rushing. Karlos Williams scored on a 1-yard run as the Bills overcame an injury-depleted offense playing without running back LeSean McCoy.
Rookie linebacker A.J. Tarpley had an interception and sealed the win by forcing Lucky Whitehead to fumble on the kickoff return that followed Gillislee's touchdown.
Buffalo (7-8) snapped a two-game skid and won for just the second time in six games.
The Cowboys (4-11) lost in quarterback Kellen Moore's first career start. Moore went 13 of 31 for 186 yards and an interception. Dan Bailey had two field goals for Dallas.